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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZAP70
All Species:
10
Human Site:
T300
Identified Species:
20
UniProt:
P43403
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43403
NP_001070.2
619
69872
T300
T
P
E
P
A
R
I
T
S
P
D
K
P
R
P
Chimpanzee
Pan troglodytes
XP_515637
619
69840
T300
T
P
E
P
A
R
V
T
S
P
D
K
P
R
P
Rhesus Macaque
Macaca mulatta
XP_001101570
619
69877
T300
T
P
E
P
A
R
V
T
S
P
E
K
P
R
P
Dog
Lupus familis
XP_861301
601
68596
R304
A
T
D
R
D
A
Q
R
E
A
L
P
M
D
T
Cat
Felis silvestris
Mouse
Mus musculus
P43404
618
70040
S300
E
P
A
R
L
A
S
S
T
D
K
P
R
P
M
Rat
Rattus norvegicus
Q64725
629
71510
Q304
H
K
K
P
P
P
P
Q
G
S
R
P
E
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515271
507
56102
L256
R
E
E
A
E
R
M
L
F
S
G
S
Q
P
D
Chicken
Gallus gallus
Q07494
984
109166
A512
Q
V
R
A
R
T
V
A
G
Y
G
K
Y
S
G
Frog
Xenopus laevis
Q91736
902
100832
K434
R
T
V
A
G
Y
G
K
F
S
S
K
M
C
F
Zebra Danio
Brachydanio rerio
O13146
981
109636
Q589
E
E
E
K
M
Q
F
Q
H
G
R
V
K
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24145
939
104255
N616
A
P
A
V
A
R
L
N
S
L
G
P
N
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189062
746
84636
K348
D
Y
A
G
I
D
D
K
A
V
A
Y
A
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
53.6
N.A.
93.5
53.7
N.A.
57.6
22.6
24.2
25.2
N.A.
25.1
N.A.
N.A.
34
Protein Similarity:
100
100
98.3
70.4
N.A.
96.1
70.9
N.A.
62.6
35.5
39.1
37.4
N.A.
40.8
N.A.
N.A.
49.4
P-Site Identity:
100
93.3
86.6
0
N.A.
6.6
6.6
N.A.
13.3
6.6
6.6
13.3
N.A.
26.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
20
13.3
N.A.
20
13.3
6.6
20
N.A.
33.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
25
25
34
17
0
9
9
9
9
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
0
9
0
9
9
9
0
0
9
17
0
0
9
9
% D
% Glu:
17
17
42
0
9
0
0
0
9
0
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
9
% F
% Gly:
0
0
0
9
9
0
9
0
17
9
25
0
0
9
9
% G
% His:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
9
% I
% Lys:
0
9
9
9
0
0
0
17
0
0
9
42
9
0
0
% K
% Leu:
0
0
0
0
9
0
9
9
0
9
9
0
0
9
0
% L
% Met:
0
0
0
0
9
0
9
0
0
0
0
0
17
0
9
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% N
% Pro:
0
42
0
34
9
9
9
0
0
25
0
34
25
17
34
% P
% Gln:
9
0
0
0
0
9
9
17
0
0
0
0
9
0
0
% Q
% Arg:
17
0
9
17
9
42
0
9
0
0
17
0
9
25
0
% R
% Ser:
0
0
0
0
0
0
9
9
34
25
9
9
0
17
9
% S
% Thr:
25
17
0
0
0
9
0
25
9
0
0
0
0
0
17
% T
% Val:
0
9
9
9
0
0
25
0
0
9
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
0
0
0
9
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _